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Alchemy Labs E-Guard Hormone Support Capsules 30 Servings - KSM-66® Ashwagandha Root Extract 300mg | Svpplements

Alchemy Labs

Alchemy Labs | E-Guard | 30 Capsules

Transparent hormone support with clinical KSM-66® and 150mg DIM.

$44.95 $59.99$1.49/serving
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Hand Packed Climate-controlled
300mg KSM-66® Ashwagandha Root Extract
300mg Stinging Nettle Root Extract
150mg 3,3'-Diindolylmethane (DIM)
250mg Milk Thistle Seed Extract
✓ Label Verified✓ No Prop Blends✓ DSHEA Compliant
TM DIM KSM-66 KSM-66
300mg KSM-66® Ashwagandha — clinical stress support
150mg DIM — researched estrogen support range
300mg Stinging Nettle — androgen-supportive botanical
19mg Calcium D-Glucarate — elimination support
250mg Milk Thistle — liver-supportive extract
50mg Acacetin — advanced hormone-support flavone
Bioperine™ Ksm 66™
🌾 Gluten Free 🫘 Soy Free
"After a couple weeks, I felt more balanced and less run down, and it was easy to fit into my daily stack without any stim crash. It’s the kind of formula you run consistently when you want cleaner daily support instead of a quick hit."
Verified buyer
💊 Gelatin Capsules
Featuring: KSM-66® by Ixoreal BiomedBioPerine® by Sabinsa Corporation
⚠️ Allergen Information +
Contains:
Manufactured in a facility that also processes:
MilkSoyEggsWheatTree NutsPeanutsFishShellfish
SuppVault Summary

Alchemy Labs E-Guard is a fully disclosed hormone-support formula built to support estrogen metabolism, androgen balance, stress resilience, and detox capacity. It pairs 150mg DIM with 300mg KSM-66® Ashwagandha plus targeted liver and elimination support for a more complete hormonal-environment approach.

Great Fit

  • Physique athletes wanting tighter estrogen management
  • Intermediate lifters in high-volume hypertrophy blocks
  • Men seeking non-gimmicky hormone support
  • Users wanting stress and hormone support together
  • Athletes chasing a harder, drier look
  • Lifters wanting liver support with hormone support
  • Experienced supplement users avoiding mystery blends

Not Ideal If

  • Anyone under 18 should avoid hormone-support formulas.
  • Pregnant or nursing women should not use this product.
  • Anyone with hormone-sensitive conditions should ask a clinician first.
  • Users taking endocrine, prostate, or estrogen-related medications need medica...
  • Those sensitive to botanical extracts should start cautiously.
Have a question about this product?
When With meals
Time Any time
What You'll Feel
Days 1-3
Subtle start; stress response may feel calmer.
Days 4-7
Baseline feels steadier without any stimulant-like kick.
🎯
Week 2
Recovery rhythm and day-to-day composure become more noticeable.
Weeks 2-3
Body-composition support may show through a tighter look.
Weeks 3-4
Hormone-support benefits become clearer with consistent use.
🎯
Ongoing
Best results come from daily use with meals.

Deep Dive

Adaptogen 1
Ka
KSM-66® Ashwagandha Root Extract
300mg
Clinical
Hormone 4
Xa
Stinging Nettle Root Extract
300mg
Ud
Calcium D-Glucarate
150mg
Di
3,3'-Diindolylmethane (DIM)
150mg
Clinical
Et
5,7-dihydroxy-4'-methoxyflavone (Acacetin)
50mg
Clinical
Anti oxidant 2
Gs
Grape Seed Extract
250mg
Cv
Citrus Bioflavonoids
200mg
Anti inflammatory 1
Ki
Milk Thistle Seed Extract
250mg
Vitamin 1
Ca
Calcium
Below
ADA: 1HOR: 4ANT: 2ANT: 1VIT: 1
KSM-66® Ashwagandha Root Extract
KSM-66®Clinical Dose
300mg
Clinical range: 300-600mg
adaptogen
150mg
Clinical range: 100-300mg
hormone
50mg
Clinical range: insufficient data
hormone
Stinging Nettle Root Extract
Under-Researched
300mg
Clinical range: unknown
hormone
Milk Thistle Seed Extract
Under-Researched
250mg
Clinical range: unknown
recovery
Grape Seed Extract
Under-Researched
250mg
Clinical range: unknown
recovery
Citrus Bioflavonoids
Under-Researched
200mg
Clinical range: unknown
recovery
Calcium D-Glucarate
Under-Researched
150mg
Clinical range: unknown
hormone

Calcium

Form: as Calcium D-Glucarate
19mg Dose
1% Daily Value
Disclosed Transparency
View full research →

KSM-66® Ashwagandha (Withania somnifera) Root Extract

300mg Dose
Daily Value
Disclosed Transparency
View full research →

Stinging Nettle (Urtica dioica) Root Extract

300mg Dose
Daily Value
Disclosed Transparency
View full research →

Grape (Vitis vinifera) Seed Extract (std. to Proanthocyanidin)

250mg Dose
Daily Value
Disclosed Transparency
View full research →

Milk Thistle (Silybum marianum) Seed Extract (std. to Silymarin)

250mg Dose
Daily Value
Disclosed Transparency
View full research →

Citrus Bioflavonoids (Citrus aurantium) Immature Fruit Extract (std. to Hesperidin)

200mg Dose
Daily Value
Disclosed Transparency
View full research →

Calcium D-Glucarate

150mg Dose
Daily Value
Disclosed Transparency
View full research →

3,3'-Diindolylmethane (DIM)

150mg Dose
Daily Value
Disclosed Transparency
View full research →

5,7-dihydroxy-4'-methoxyflavone (Acacetin)

50mg Dose
Daily Value
Disclosed Transparency
View full research →

BioPerine® Black Pepper (Piper nigrum) Fruit Extract (std. to min. 95% Piperine)

5mg Dose
Daily Value
Disclosed Transparency
View full research →
BASE Alchemy Labs | E-Guard | 30 Capsules
$44.95
Alchemy Labs | Creatine Mono | 75 Servings
$34.95$0.46/srv 75 servings

E-Guard targets hormonal environment and stress adaptation, not phosphocreatine storage. Adding a standalone creatine monohydrate gives you the clinically established ATP-recycling support for strength, power output, and lean mass that complements E-Guard’s recovery and hormone-support role.

Take daily at any time; can be taken with E-Guard or post-workout.

Whey Isolate or Hydrolyzed ProteinPROTEIN

Hormone-support supplements work best when the fundamentals are already covered, and protein intake is one of the biggest fundamentals. Pairing E-Guard with a high-quality protein helps provide the amino acid substrate for recovery and muscle repair while E-Guard supports the internal stress and hormone environment around that process.

Use post-workout or any time daily protein intake is falling short.

Omega-3 Fish OilGENERAL WELLNESS

Fish oil pairs well with E-Guard because both formulas support the broader internal environment rather than the same narrow mechanism. Omega-3s help support inflammatory balance, cardiovascular health, and recovery quality, complementing E-Guard’s use of grape seed extract, citrus bioflavonoids, and milk thistle.

Take with meals; can be taken alongside E-Guard.

Magnesium GlycinateSLEEP

KSM-66® Ashwagandha already addresses stress adaptation, and magnesium glycinate can strengthen that recovery-focused strategy by supporting relaxation, sleep quality, and neuromuscular function. This is an especially smart stack for lifters whose poor recovery is driven as much by life stress and suboptimal sleep as by training volume.

Take in the evening or before bed; E-Guard can be taken earlier with a meal.

Electrolyte Hydration FormulaHYDRATION ELECTROLYTE

E-Guard is not a hydration product, but hard-training athletes often feel better overall when endocrine support is paired with better fluid and mineral management. An electrolyte formula helps training output, pumps, and recovery while E-Guard handles the slower-moving stress and hormone-support side.

Use pre-, intra-, or post-workout depending on sweat loss and session length.

Stack Total
calculating...
Per Day
Includes base product + selected items
Alchemy Labs | E-Guard | 30 Capsules93
$44.95
This Product
$/srv: $1.67
This Product Wins

E-Guard looks more targeted for estrogen metabolism and daily hormonal-environment support.

$/srv: $1.50
This Product Wins

E-Guard has a more specialized architecture for estrogen, stress, and liver support.

$/srv: $1.83
Them

Poise has stronger category recognition and reputation in targeted hormone support.

$/srv: $1.60
Tie

Both aim at hormone support, but E-Guard appears broader while Estrozole may be more singularly focused.

Clinical Dosing

KSM-66® Ashwagandha Root Extract 300mg
Stinging Nettle Root Extract 300mg
3,3'-Diindolylmethane (DIM) 150mg
Milk Thistle Seed Extract 250mg
Full Product Description Article

Alchemy Labs E-Guard is a hormone-support capsule formula designed around one clear objective: improve the terrain around estrogen metabolism, androgen availability, stress resilience, and detox capacity rather than chasing gimmicky “test booster” marketing. The formulation strategy is more sophisticated than most products in this category. Instead of relying on one or two trendy actives, E-Guard combines multiple pathways: estrogen metabolite balance via DIM, elimination support via calcium D-glucarate, androgen-supportive botanicals like stinging nettle root and acacetin, stress modulation from KSM-66® ashwagandha, and antioxidant/liver support from grape seed, milk thistle, and citrus bioflavonoids.

KSM-66® Ashwagandha is included at 300mg, which lands directly inside the clinical range of 300-600mg. This matters. KSM-66® is not generic ashwagandha powder; it is a full-spectrum root extract standardized to 5% withanolides and backed by 24 double-blind, randomized, placebo-controlled trials. Mechanistically, it modulates the HPA axis and helps lower cortisol, which is relevant because chronically elevated cortisol can work against recovery, mood, sleep quality, and favorable hormone status. In practice, this is the part of the formula many users feel as improved stress tolerance, more stable energy, and less “wired but depleted” recovery.

DIM at 150mg is another strong inclusion because it sits squarely within the researched 100-200mg range. DIM is a bioactive compound derived from cruciferous vegetable metabolism and is used for its ability to shift estrogen metabolism toward a more favorable balance of metabolites, especially away from more proliferative pathways and toward 2-hydroxyestrone. It also shows mild aromatase-modulating activity. This is not an overnight-feel ingredient; it is a consistency ingredient that supports the internal hormonal environment over time.

Acacetin at 50mg also deserves attention because that is exactly where the limited but relevant sports supplement literature typically places it: 50-75mg. Its primary use here is as a natural aromatase-inhibiting flavone, helping reduce the conversion of androgens to estrogen. Human evidence is still limited, so the honest take is that this is a mechanistically intelligent inclusion rather than a clinically proven slam dunk. Still, at 50mg it is not pixie dusted.

Calcium D-glucarate at 150mg is the weakest dose in the formula relative to how it is often used in estrogen-support products, where larger doses are common. Its role is to support glucuronidation and the elimination side of estrogen metabolism, helping the body package and excrete compounds efficiently. It still fits the architecture, but it is fair to say this is a supportive dose rather than an aggressive standalone dose. The listed 19mg calcium contributed from calcium d-glucarate is nutritionally insignificant and should not be viewed as meaningful calcium supplementation.

Stinging nettle root extract at 300mg is a classic inclusion in this category for androgen support, often discussed for its interaction with sex hormone-binding globulin and prostate-related pathways. Grape seed extract at 250mg standardized to proanthocyanidins provides antioxidant support and may complement vascular and inflammatory health. Milk thistle seed extract at 250mg standardized to silymarin supports liver function, which matters because hormone metabolism and clearance are liver-dependent processes. Citrus bioflavonoids at 200mg standardized to hesperidin add additional polyphenol support for vascular and oxidative balance.

The formula is fully disclosed with no proprietary blend, which is a major advantage in a category full of labels that hide underdosed actives. Day 1, this is not a stimulant-style “feel it in 20 minutes” product. Expect a subtle profile: possibly calmer stress response from KSM-66® and no dramatic acute sensation. Over 2-4 weeks, the formula’s intended payoff is better hormonal balance support, improved composure under training stress, less recovery drag, and a tighter, more consistent day-to-day feel when diet and training are already in order.

Science & Clinical References 11 citations
DIM and Estrogen Metabolite Balance3 studies

DIM is a cruciferous-derived indole metabolite studied for its ability to influence estrogen biotransformation pathways. Mechanistically, it may help shift phase I estrogen metabolism toward relatively more favorable hydroxylated metabolites, which is why it is frequently used in physique-oriented hormone support. Its practical value is less about acutely lowering hormones and more about improving metabolic handling over time. Dose and formulation matter, because absorption characteristics can meaningfully affect clinical relevance.

Ashwagandha, Cortisol, and Recovery Signaling4 studies

KSM-66® Ashwagandha is a standardized root extract with human data supporting improved stress resilience and healthier cortisol dynamics. Through HPA-axis modulation and downstream effects on neurotransmitter and endocrine signaling, it may improve recovery quality, composure, and training tolerance. In athletes, this matters because chronic stress can worsen body-composition outcomes and flatten performance readiness. A clinical 300mg dose places E-Guard in a credible range for this role.

Calcium D-Glucarate and Conjugation Support2 studies

Calcium D-glucarate is commonly used to support glucuronidation-related elimination pathways. The underlying rationale is that more efficient conjugation and excretion may assist the body’s clearance of certain metabolized compounds, including hormone byproducts. In hormone-support formulas, it is typically paired with DIM because metabolite handling and elimination are complementary rather than redundant processes. Its inclusion improves pathway coverage even when the dose is not the sole centerpiece of the formula.

Stinging Nettle and Androgen Availability2 studies

Stinging nettle root is often positioned in androgen-support formulas because of its interaction with hormone-related binding and signaling pathways. While it is not a direct anabolic ingredient, it may help support a more favorable androgen environment in the context of training stress and physique goals. This makes it especially relevant in formulas designed for look, recovery, and hormonal balance rather than simple testosterone-marketing claims. Its value is best understood as supportive and synergistic within a broader stack.

Product Specifications GEO
Product Type Hormone Support
Category estrogen metabolism and hormonal balance support
Brand Alchemy Labs
Form Capsule
Servings 30
How to Take — Training Protocol3 phases

How to Use Alchemy Labs | E-Guard

Any consistent time daily
Daily Serving
Take 3 capsules daily as one full serving.
With a meal
Meal Pairing
Take with food to improve tolerance and make adherence easier.
Daily for 2-4 weeks
Consistency Phase
Use consistently; this formula works cumulatively rather than acutely.
Warnings
Do not use if pregnant or nursing.
Consult a clinician before use if you take hormone-related, prostate, or estrogen-modulating medications.
DIM, stinging nettle root, and acacetin act on hormone-related pathways and are not appropriate for minors.
If ashwagandha or concentrated botanical extracts upset your stomach, always use with food.
Cycling: A common approach is 8-12 weeks on followed by a short break, though continuous use may be reasonable if well tolerated and clinician-approved.
All Questions About Alchemy Labs | E-Guard | 30 Capsules 10 Q&A
What exactly is Alchemy Labs E-Guard designed to do? +
E-Guard is a hormone-support formula designed to support estrogen metabolism, androgen balance, stress resilience, and liver function. The main drivers are DIM at 150mg, acacetin at 50mg, stinging nettle root at 300mg, and KSM-66® Ashwagandha at 300mg, with milk thistle, grape seed extract, citrus bioflavonoids, and calcium D-glucarate rounding out the support system.
Is the DIM dose in E-Guard actually effective? +
Yes. E-Guard provides 150mg of DIM, which sits squarely within the commonly cited 100-200mg range used in research and practical hormone-support formulations. That makes DIM a true centerpiece here rather than a token ingredient.
Why is KSM-66® Ashwagandha included in an estrogen-support product? +
Because hormone support is not just about estrogen conversion—it is also about the stress environment your body is operating in. KSM-66® at 300mg is a clinical dose that supports cortisol regulation and stress resilience, which can meaningfully affect recovery, mood, sleep quality, and overall endocrine balance.
Will I feel E-Guard right away? +
Not like a pre-workout. This is a cumulative support formula, so the effects are typically more noticeable over 2-4 weeks of consistent daily use rather than within an hour of taking it. The earliest thing some users notice is better stress composure from the KSM-66® portion.
Is E-Guard fully transparent or does it use a proprietary blend? +
It is fully transparent. Every active ingredient and dose is disclosed on the label, including KSM-66® Ashwagandha 300mg, DIM 150mg, calcium D-glucarate 150mg, and acacetin 50mg. That is a major advantage in this category.
How should I take Alchemy Labs E-Guard? +
Take 3 capsules daily with a meal. Because the formula works through cumulative hormone and stress-support pathways, the best practice is simply taking it consistently at the same time each day rather than treating it like a pre-workout.
Can I stack E-Guard with a pre-workout or test booster? +
You can stack it with a pre-workout because E-Guard is stim-free and does not add caffeine. Be more careful with other hormone products, though, especially if they also contain DIM, aromatase-focused ingredients, or additional ashwagandha, because overlap can become unnecessary or excessive.
Is calcium D-glucarate well dosed in this formula? +
It is included at 150mg, which supports the formula’s elimination and glucuronidation concept, but this is better described as a supportive dose than an aggressive standalone dose. It makes sense in the stack, but it is not the primary hero ingredient here.
Does this product contain caffeine or stimulants? +
No meaningful stimulants are disclosed in the verified formula. Despite the metadata error, this is functionally a stim-free capsule formula focused on hormone and stress support, not acute energy.
How does this compare to stripped-down retail versions? +
This verified version is more complete. Competitive landscape data indicates some marketplace versions remove ingredients such as KSM-66®, stinging nettle root, grape seed extract, milk thistle, and calcium contribution from calcium d-glucarate, which reduces the formula’s stress-support, antioxidant, and liver-support depth.

* These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease. Consult your physician before use if you have a medical condition or take medications.

Quick Answers

What exactly is Alchemy Labs E-Guard designed to do?

E-Guard is a hormone-support formula designed to support estrogen metabolism, androgen balance, stress resilience, and liver function. The main drivers are DIM at 150mg, acacetin at 50mg, stinging nettle root at 300mg, and KSM-66® Ashwagandha at 300mg, with milk thistle, grape seed extract, citrus bioflavonoids, and calcium D-glucarate rounding out the support system.

Is the DIM dose in E-Guard actually effective?

Yes. E-Guard provides 150mg of DIM, which sits squarely within the commonly cited 100-200mg range used in research and practical hormone-support formulations. That makes DIM a true centerpiece here rather than a token ingredient.

Why is KSM-66® Ashwagandha included in an estrogen-support product?

Because hormone support is not just about estrogen conversion—it is also about the stress environment your body is operating in. KSM-66® at 300mg is a clinical dose that supports cortisol regulation and stress resilience, which can meaningfully affect recovery, mood, sleep quality, and overall endocrine balance.

Will I feel E-Guard right away?

Not like a pre-workout. This is a cumulative support formula, so the effects are typically more noticeable over 2-4 weeks of consistent daily use rather than within an hour of taking it. The earliest thing some users notice is better stress composure from the KSM-66® portion.

Is E-Guard fully transparent or does it use a proprietary blend?

It is fully transparent. Every active ingredient and dose is disclosed on the label, including KSM-66® Ashwagandha 300mg, DIM 150mg, calcium D-glucarate 150mg, and acacetin 50mg. That is a major advantage in this category.

How should I take Alchemy Labs E-Guard?

Take 3 capsules daily with a meal. Because the formula works through cumulative hormone and stress-support pathways, the best practice is simply taking it consistently at the same time each day rather than treating it like a pre-workout.

Can I stack E-Guard with a pre-workout or test booster?

You can stack it with a pre-workout because E-Guard is stim-free and does not add caffeine. Be more careful with other hormone products, though, especially if they also contain DIM, aromatase-focused ingredients, or additional ashwagandha, because overlap can become unnecessary or excessive.

Is calcium D-glucarate well dosed in this formula?

It is included at 150mg, which supports the formula’s elimination and glucuronidation concept, but this is better described as a supportive dose than an aggressive standalone dose. It makes sense in the stack, but it is not the primary hero ingredient here.

Does this product contain caffeine or stimulants?

No meaningful stimulants are disclosed in the verified formula. Despite the metadata error, this is functionally a stim-free capsule formula focused on hormone and stress support, not acute energy.

How does this compare to stripped-down retail versions?

This verified version is more complete. Competitive landscape data indicates some marketplace versions remove ingredients such as KSM-66®, stinging nettle root, grape seed extract, milk thistle, and calcium contribution from calcium d-glucarate, which reduces the formula’s stress-support, antioxidant, and liver-support depth.
93

SuppVault Score

Alchemy Labs | E-Guard | 30 Capsules

💊 Clinical Dosing 10/10

9/9 key ingredients with disclosed doses

🏷 Label Transparency 10/10

Full label disclosure

🏭 Manufacturing 4/10

No manufacturing certifications found

🔬 Testing 3/10

No third-party certification found

🧪 Inactive Ingredients 10/10

No artificial colors or sweeteners

💰 Value 5/10

$1.50/serving — above $1.43 category median

Scores are relative to category averages. Proprietary blends score lower on transparency naturally — this is neutral fact, not penalty.

* These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease. Consult your physician before use if you have a medical condition or take medications.

Allergen Information +
Made in a facility that may also process products containing Milk
Eggs
Soy
Wheat
Fish
Shellfish
Tree Nuts
Peanuts
and Sesame.
Contains:
Made in a facility that may also process products containing MilkEggsSoyWheatFishShellfishTree NutsPeanutsand Sesame.
Sport & Athlete Compliance +
HS — Contains Banned SubstanceNCAA — Contains Banned SubstanceWADA Prohibited

Sport compliance status is computed by cross-referencing this product's ingredient panel against the NCAA 2025-26 Banned Substances List, WADA Prohibited List, and state high school athletic association guidelines. Banned substance lists are updated periodically by their governing bodies. This information is provided for reference only and may not reflect the most current list. Always verify with your organization, coach, or compliance officer before use. SuppVault is not responsible for eligibility decisions.

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