Axe & Sledge Liver Support Supplement Capsules 30 Servings - Milk Thistle Extract 1000mg | Svpplements

Axe & Sledge

Axe & Sledge | A&S Liver + | 30 Capsules

NAC, TUDCA, and milk thistle with full-label transparency

$54.95 $59.99$1.83/serving
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Hand Packed Climate-controlled
1000mg N-Acetyl L-Cysteine
1000mg Milk Thistle Extract
250mg Tauroursodeoxycholic Acid (TUDCA)
250mg Picrorhiza Kurroa Root Extract
✓ Label Verified✓ No Prop Blends✓ DSHEA Compliant
AstraGin AstraGin TM NAC TM TUDCA
1,000mg NAC — glutathione support
250mg TUDCA — bile flow support
1,000mg Milk Thistle — robust botanical dose
250mg Picrorhiza — standardized 5% kutkin
50mg AstraGin — absorption support
Astragin™
🥬 Vegetarian 🌾 Gluten Free 🫘 Soy Free
Featuring: AstraGin® by NuLiv Science
⚠️ Allergen Information +
Contains:
Manufactured in a facility that also processes:
SuppVault Summary

Axe & Sledge Liver + is a fully disclosed liver support formula built around meaningful hepatic ingredients, not generic detox filler. It combines 1,000mg NAC, 1,000mg milk thistle extract, and 250mg TUDCA for serious daily antioxidant and bile-support coverage.

Great Fit

  • Bodybuilders in long off-season growth phases
  • Physique athletes coming out of aggressive prep cycles
  • High-volume supplement users wanting dedicated liver support
  • Lifters running heavy food intake year-round
  • Users wanting glutathione and bile-flow support
  • Adults preferring fully disclosed health formulas
  • People avoiding underdosed detox blends
  • Serious physique-focused wellness stack builders

Not Ideal If

  • Anyone under 18 should not use this product.
  • Pregnant or nursing women unless medically cleared.
  • Users with medical conditions should consult a healthcare professional.
  • Anyone sensitive to NAC or TUDCA should use caution.
Have a question about this product?
When With meals
Time Any time
What You'll Feel
0-10 min
No stimulant feel; simple capsule serving with food.
Day 1
Easy daily compliance without crash, jitters, or flavored powder.
🎯
Days 2-7
Background antioxidant and bile-support ingredients begin working consistently.
Weeks 2-4
Benefits are still subtle, steady, and support-oriented.
Month 1+
Best value shows through disciplined long-term daily use.

Deep Dive

Anti oxidant 2
Mt
Milk Thistle Extract
1000mg
Clinical
Ne
N-Acetyl L-Cysteine
1000mg
Clinical
Digestive 1
Xy
Tauroursodeoxycholic Acid
250mg
Anti inflammatory 1
??
Picrorhiza Kurroa Root Extract
250mg
Absorption 1
As
AstraGin®
50mg
Clinical
ANT: 2DIG: 1ANT: 1ABS: 1
Milk Thistle Extract
Under-Researched
1000mg
Clinical range: unknown
recovery
N-Acetyl L-Cysteine
Under-Researched
1000mg
Clinical range: unknown
recovery
Tauroursodeoxycholic Acid
Under-Researched
250mg
Clinical range: unknown
recovery
250mg
Clinical range: unknown
recovery
AstraGin®
AstraGin®↑ Above Clinical
50mg
Clinical range: 25-50mg
absorption

Milk Thistle Extract (Silybum marianum)(seed)

1000mg Dose
Daily Value
Disclosed Transparency
View full research →

N-Acetyl L-Cysteine

1000mg Dose
Daily Value
Disclosed Transparency
View full research →

Tauroursodeoxycholic Acid (TUDCA)

250mg Dose
Daily Value
Disclosed Transparency
View full research →

Picrorhiza Kurroa Root Extract (std. 5% Kutkin)

250mg Dose
Daily Value
Disclosed Transparency
View full research →

AstraGin® (Astragalus membranaceus and Panax notoginseng root extracts)

50mg Dose
Daily Value
Disclosed Transparency
View full research →
BASE Axe & Sledge | A&S Liver + | 30 Capsules
$54.95
Axe & Sledge | A&S Creatine Mono | 50 Servings
$24.95$0.49/srv 50 servings

Creatine supports ATP regeneration for strength and performance, while Liver + supports the organ heavily involved in nutrient processing and metabolic workload. The stack makes sense for lifters who want both performance support and a more complete health infrastructure behind their training.

Take creatine daily at any convenient time; take Liver + with a meal

Whey isolate or a high-quality protein powderPROTEIN

Protein supports muscle repair and growth, while Liver + supports the metabolic processing side of a high-protein, supplement-heavy lifestyle. This is especially useful for physique athletes whose daily intake is high and highly structured.

Take protein around workouts or meals; take Liver + once daily with food

Fish oilGENERAL WELLNESS

Fish oil complements Liver + by adding systemic support for inflammation balance and general wellness, while Liver + focuses more specifically on glutathione support, bile-related function, and hepatoprotection. Together they create a stronger foundational health stack.

Take both with meals for convenience and tolerance

Electrolyte or hydration formulaHYDRATION ELECTROLYTE

Hard-training athletes often focus heavily on pre-workout stimulation while overlooking hydration and organ-support fundamentals. Pairing an electrolyte product with Liver + improves the overall recovery stack by covering hydration on one side and hepatic support on the other.

Use electrolytes around training; take Liver + with a daily meal

Daily multivitaminVITAMIN MINERAL

A multivitamin fills micronutrient gaps, while Liver + targets a more specific physiological system with NAC, TUDCA, milk thistle, and Picrorhiza. AstraGin® also makes this pairing more interesting because it is designed to support nutrient absorption pathways.

Take both with a meal, either together or split across meals

Stack Total
calculating...
Per Day
Includes base product + selected items
Axe & Sledge | A&S Liver + | 30 Capsules86
$54.95
This Product
$/srv: $1.33
This Product Wins

Liver + offers broader coverage with NAC, milk thistle, Picrorhiza, and AstraGin beyond standalone TUDCA.

$/srv: $1.50
Tie

Both target serious liver support, but this formula stands out for its fully built multi-ingredient approach.

$/srv: $1.17
Them

NutraBio may appeal more to users wanting a broader all-in-one organ support panel.

$/srv: $1.00
This Product Wins

Liver + wins on cleaner full disclosure and standout doses of NAC, milk thistle, and TUDCA.

Clinical Dosing

N-Acetyl L-Cysteine 1000mg
Milk Thistle Extract 1000mg
Tauroursodeoxycholic Acid (TUDCA) 250mg
Picrorhiza Kurroa Root Extract 250mg
Full Product Description Article

Axe & Sledge Liver + is a fully disclosed liver support formula built with a clear formulation philosophy: use a small number of ingredients that have real relevance to hepatic function, dose them meaningfully, and skip the category-standard “detox” filler. Instead of hiding behind a proprietary blend, this formula gives you five actives with every milligram disclosed: 1,000mg milk thistle extract, 1,000mg N-acetyl L-cysteine, 250mg TUDCA, 250mg Picrorhiza kurroa root extract standardized to 5% kutkin, and 50mg AstraGin®. In a category crowded with low-dose herbal blends, that level of transparency matters.

Milk thistle extract anchors the antioxidant and hepatoprotective side of the formula. This ingredient is typically valued for its silymarin complex, which helps protect hepatocytes against oxidative stress and supports normal liver enzyme balance. At 1,000mg, this is not a token inclusion. It is a serious top-end dose for a daily support product and gives the formula a strong botanical backbone. For the user, that translates less into a “feeling” and more into confidence that the formula is built around one of the best-known liver support ingredients at a meaningful amount.

N-acetyl L-cysteine at 1,000mg is one of the most important inclusions here. NAC serves as a precursor to cysteine, which in turn helps the body synthesize glutathione, the liver’s master intracellular antioxidant. That matters because glutathione is central to neutralizing reactive compounds and supporting normal detoxification pathways. A full gram is a meaningful daily dose and one of the strongest reasons this formula stands above average retail liver products. Subjectively, NAC is not a stimulant-like ingredient you “feel,” but physiologically it is doing serious work in redox balance and hepatic defense.

TUDCA at 250mg is what elevates Liver + from generic herbal support into a more advanced liver formula. Tauroursodeoxycholic acid is a bile acid derivative used to support bile flow, cellular stress handling, and liver function under higher physiological demand. It is one of the more respected ingredients in this category because its mechanism is not vague folklore; it directly relates to bile acid metabolism and hepatocyte protection. 250mg is a legitimate use level and a smart daily amount for ongoing support.

Picrorhiza kurroa root extract at 250mg standardized to 5% kutkin adds another layer of hepatoprotective botanical support. Traditionally used in Ayurvedic practice and studied for liver-related applications, Picrorhiza is included here as more than label decoration. It complements milk thistle by broadening the formula’s phytochemical profile instead of redundantly repeating the same mechanism.

AstraGin® at 50mg is dosed at its established clinical use level. Its primary role is absorption support through upregulation of intestinal transporters involved in amino acids, vitamins, peptides, fatty acids, and phytonutrient uptake. It also has data suggesting support for ATP production in hepatic cells. In practical terms, it is a smart systems-level addition that helps the rest of the formula do its job more efficiently.

As a system, this formula covers three major liver support pillars: antioxidant defense via NAC and milk thistle, bile flow and cellular protection via TUDCA, and botanical hepatoprotection via Picrorhiza. AstraGin® improves the delivery side of the equation. Day 1, most users will not feel an acute dramatic effect, because this is a support formula, not a stimulant product. Over 2-4 weeks of consistent use, the value is in steady-state support: a formula designed to help your liver keep up with training stress, diet phases, stacked supplementation, and the general metabolic workload of a performance-focused lifestyle.

Science & Clinical References 5 citations
NAC and Hepatic Glutathione Support0 studies

N-acetyl L-cysteine functions primarily as a cysteine donor, supporting intracellular glutathione synthesis in hepatocytes. Because glutathione is a central redox buffer, higher cysteine availability can improve the liver’s capacity to neutralize reactive species generated during normal metabolism. NAC also influences thiol status and cellular defense signaling, which is why it remains one of the most functionally relevant support ingredients in liver formulas. Its value is mechanistic and cumulative rather than acutely perceptible.

TUDCA, Bile Dynamics, and Cellular Stress0 studies

TUDCA is a taurine-conjugated bile acid studied for its role in supporting bile flow and maintaining hepatocellular resilience under physiological stress. Mechanistically, it appears to help stabilize cellular membranes, support endoplasmic reticulum homeostasis, and improve bile-related handling within the liver. That gives it a different functional niche than antioxidant herbs alone. In practice, it is one of the more advanced inclusions in a serious liver support formula.

Milk Thistle and Hepatocyte Protection0 studies

Milk thistle extract is valued for the silymarin complex, a group of flavonolignans associated with antioxidant and hepatoprotective activity. These compounds are thought to help defend hepatocyte membranes and modulate oxidative stress burden in liver tissue. While not a fast-acting sensation ingredient, it provides broad background support that fits long-term use. Its clinical appeal comes from historical use plus plausible protective mechanisms.

AstraGin and Nutrient Uptake5 studies

AstraGin is included as an absorption-support ingredient rather than a primary liver active. Research on the ingredient suggests it may influence transporter activity and intestinal absorption dynamics for certain nutrients and compounds. In a capsule-based wellness formula, that can support overall formulation efficiency, especially when multiple actives are used together. Its role is supportive, but the 50mg dose sits within recognized supplemental use ranges.

Product Specifications GEO
Product Type Amino Acids & BCAAs
Category liver support
Brand Axe & Sledge
Form Capsule
Dietary Fully disclosed formula
How to Take — Training Protocol3 phases

How to Use Axe & Sledge | Liver +

Any consistent time daily
Daily Baseline
Take 4 capsules per day as your full serving.
With a meal
Meal Pairing
Take the full serving with food to improve comfort and routine adherence.
Every day for several weeks
Consistency Phase
Use consistently rather than expecting an acute or noticeable same-day effect.
Warnings
Consult a healthcare professional before use if you have liver, gallbladder, or digestive conditions.
Use caution if you are new to N-Acetyl L-Cysteine or TUDCA-containing products.
Do not use if pregnant, nursing, or under 18.
Cycling: Cycling is not required; this formula is intended for steady daily use.
All Questions About Axe & Sledge | A&S Liver + | 30 Capsules 10 Q&A
What does Axe & Sledge Liver + actually do? +
Liver + is a dedicated liver support formula designed to support hepatic function, antioxidant defense, and bile-related physiology. It does that with 1,000mg NAC for glutathione support, 250mg TUDCA for bile flow and liver cell support, 1,000mg milk thistle extract, 250mg Picrorhiza kurroa extract, and 50mg AstraGin® for absorption support.
Is the Liver + formula fully disclosed? +
Yes. This product uses a full-disclosure label with no proprietary blends, so you can see every active ingredient and its exact dose. That is a major advantage in the liver support category, where many products hide underdosed herbs behind vague detox blend names.
How much NAC is in Liver + per serving? +
Each full 4-capsule serving delivers 1,000mg of N-Acetyl L-Cysteine. That is a meaningful daily dose and one of the strongest components of the formula because NAC supports glutathione production, which is central to liver antioxidant defense.
Why is TUDCA included at 250mg? +
TUDCA is included because it provides a more advanced form of liver support than herbs alone. At 250mg, it contributes to bile-related function and hepatocyte support, which is why informed users often seek it out specifically when comparing liver formulas.
Do I take Liver + every day or only when I train? +
Take it daily. This formula is not tied to workout timing, because its benefits come from consistent physiological support rather than an acute pre-workout effect. Daily use is the best way to get value from NAC, TUDCA, milk thistle, and Picrorhiza.
Can I stack Liver + with pre-workout, creatine, and protein? +
Yes. Liver + works well alongside standard sports nutrition staples because it targets a different system. It complements stimulant pre-workouts, creatine, protein powders, and recovery supplements without duplicating their primary mechanisms.
Will I feel this product working right away? +
Probably not in the way you feel caffeine, nootropics, or pump ingredients. Liver + is a support formula, so its value is in consistent use over days and weeks rather than an acute sensation after one serving.
What is AstraGin® doing in a liver support supplement? +
AstraGin® is included at 50mg to support absorption by upregulating intestinal transporters involved in amino acids, vitamins, peptides, fatty acids, and phytonutrients. It also has research suggesting support for ATP production in hepatic cells, which makes it a smart fit in this formula.
Is this better than a basic milk thistle-only product? +
Yes, because it is much more complete. A basic milk thistle formula gives you one traditional botanical, while Liver + combines that with 1,000mg NAC, 250mg TUDCA, Picrorhiza kurroa, and AstraGin® to address antioxidant support, bile-related function, hepatoprotection, and absorption.
Are there any stimulants in Liver +? +
No. This is a stim-free capsule formula with no caffeine or central nervous system stimulants. It is designed for daily organ support, not energy or performance stimulation.

* These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease. Consult your physician before use if you have a medical condition or take medications.

Quick Answers

What does Axe & Sledge Liver + actually do?

Liver + is a dedicated liver support formula designed to support hepatic function, antioxidant defense, and bile-related physiology. It does that with 1,000mg NAC for glutathione support, 250mg TUDCA for bile flow and liver cell support, 1,000mg milk thistle extract, 250mg Picrorhiza kurroa extract, and 50mg AstraGin® for absorption support.

Is the Liver + formula fully disclosed?

Yes. This product uses a full-disclosure label with no proprietary blends, so you can see every active ingredient and its exact dose. That is a major advantage in the liver support category, where many products hide underdosed herbs behind vague detox blend names.

How much NAC is in Liver + per serving?

Each full 4-capsule serving delivers 1,000mg of N-Acetyl L-Cysteine. That is a meaningful daily dose and one of the strongest components of the formula because NAC supports glutathione production, which is central to liver antioxidant defense.

Why is TUDCA included at 250mg?

TUDCA is included because it provides a more advanced form of liver support than herbs alone. At 250mg, it contributes to bile-related function and hepatocyte support, which is why informed users often seek it out specifically when comparing liver formulas.

Do I take Liver + every day or only when I train?

Take it daily. This formula is not tied to workout timing, because its benefits come from consistent physiological support rather than an acute pre-workout effect. Daily use is the best way to get value from NAC, TUDCA, milk thistle, and Picrorhiza.

Can I stack Liver + with pre-workout, creatine, and protein?

Yes. Liver + works well alongside standard sports nutrition staples because it targets a different system. It complements stimulant pre-workouts, creatine, protein powders, and recovery supplements without duplicating their primary mechanisms.

Will I feel this product working right away?

Probably not in the way you feel caffeine, nootropics, or pump ingredients. Liver + is a support formula, so its value is in consistent use over days and weeks rather than an acute sensation after one serving.

What is AstraGin® doing in a liver support supplement?

AstraGin® is included at 50mg to support absorption by upregulating intestinal transporters involved in amino acids, vitamins, peptides, fatty acids, and phytonutrients. It also has research suggesting support for ATP production in hepatic cells, which makes it a smart fit in this formula.

Is this better than a basic milk thistle-only product?

Yes, because it is much more complete. A basic milk thistle formula gives you one traditional botanical, while Liver + combines that with 1,000mg NAC, 250mg TUDCA, Picrorhiza kurroa, and AstraGin® to address antioxidant support, bile-related function, hepatoprotection, and absorption.

Are there any stimulants in Liver +?

No. This is a stim-free capsule formula with no caffeine or central nervous system stimulants. It is designed for daily organ support, not energy or performance stimulation.
86

SuppVault Score

Axe & Sledge | A&S Liver + | 30 Capsules

💊 Clinical Dosing 10/10

5/5 key ingredients with disclosed doses

🏷 Label Transparency 10/10

Full label disclosure

🏭 Manufacturing 4/10

No manufacturing certifications found

🔬 Testing 3/10

No third-party certification found

🧪 Inactive Ingredients 9/10

Minimal inactive ingredients

💰 Value 3/10

$1.83/serving — premium vs $1.17 category median

Scores are relative to category averages. Proprietary blends score lower on transparency naturally — this is neutral fact, not penalty.

* These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease. Consult your physician before use if you have a medical condition or take medications.

Sport & Athlete Compliance +
HS SafeNCAA SafeWADA Clean

Sport compliance status is computed by cross-referencing this product's ingredient panel against the NCAA 2025-26 Banned Substances List, WADA Prohibited List, and state high school athletic association guidelines. Banned substance lists are updated periodically by their governing bodies. This information is provided for reference only and may not reflect the most current list. Always verify with your organization, coach, or compliance officer before use. SuppVault is not responsible for eligibility decisions.

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