Core Nutritionals
Core Nutritionals | Poise | 28 Capsules
DIM, Vitex, Setria® and thyroid support in one transparent formula
$44.49 $1.58/serving
BioPerine™
Setria™
TM TRAACS™
• Dairy-Free⚠️ Allergen Information +
SuppVault Summary
Core Nutritionals Poise is a stimulant-free female hormone support formula for thyroid function, estrogen metabolism, and cycle-related steadiness. It combines 200mg DIM with chaste tree, iodine, magnesium, antioxidant support, and anti-inflammatory polyphenols for a more predictable monthly baseline.
Great Fit
- Women wanting steadier training across menstrual cycle phases
- Women with cycle-related mood, water, and recovery shifts
- High-stress women seeking more predictable hormone support
- Women wanting stimulant-free daily hormone support
- Women prioritizing estrogen metabolism support
- Women wanting foundational thyroid-support nutrients
- Athletes seeking antioxidant support alongside hormone support
- Women preferring focused capsules over kitchen-sink formulas
Not Ideal If
- Pregnant, trying to conceive, or nursing women
- Anyone using thyroid medication without clinician supervision
- Users on hormone-related medications without medical clearance
- Anyone sensitive to chaste tree, DIM, or pregnenolone
Deep Dive
Magnesium
Iodine
Turmeric Extract (Curcuma longa) (root) (95% curcuminoids)
Olive Extract (Olea europaea) (leaf) (20% oleuropein)
Chaste Tree Extract (Vitex agnus-castus) (fruit) (1.5% agnusides)
Bioperine® (95% Black Pepper Extract)
Dose Audit
Poise includes 72mg of magnesium as a quality bisglycinate chelate, but many users will still benefit from a dedicated magnesium product to reach a more robust daily intake. This stack makes sense for women using Poise for cycle support who also want stronger support for relaxation, muscle tension, and overall magnesium sufficiency.
Take Poise with meals; additional magnesium is often best later in the day or before bed.
Fish oil complements Poise well because omega-3s support inflammatory balance from a different angle than curcumin, glutathione, and olive leaf. This creates a broader anti-inflammatory and membrane-support strategy that fits women using Poise for overall hormonal wellness.
Take with a meal, either alongside Poise or at another meal containing fats.
Vitamin D is one of the most common foundational gaps in general wellness, and it pairs especially well with a targeted formula like Poise because hormone support works best when baseline micronutrition is covered. Magnesium also participates in vitamin D metabolism, making the combination physiologically logical.
Take with a meal containing fat; can be used with Poise.
Poise handles hormonal and resilience support, but it is not a performance formula. Adding creatine gives you direct support for phosphocreatine recycling, training output, and cognitive energy while Poise works in the background on cycle and endocrine steadiness.
Any time daily; no special timing relative to Poise is required.
If your goal is better body composition, recovery, and steadier training output across the month, protein remains foundational. Poise can help make your system feel more manageable, but protein is what supplies the raw material for muscle repair and recovery.
Use around training or any time daily to help hit total protein targets.
Poise looks more clinically focused with disclosed doses and stronger foundational thyroid and antioxidant support.
Alpha may be the better pick if you want a broader male-focused hormone performance formula instead.
Poise has a cleaner fully disclosed structure and a more serious estrogen-metabolism angle.
Cycle Support may compete on simplicity and value, while Poise offers more complete multidimensional support.
Clinical Dosing
Full Product Description Article
Core Nutritionals Poise is a fully disclosed, stimulant-free hormone support formula built around a clear strategy: support healthy thyroid function, promote favorable estrogen metabolism, improve resilience to cycle-related symptom fluctuations, and reinforce antioxidant and inflammatory control. This is not a kitchen-sink multivitamin pretending to be a hormone product. It is a focused capsule formula using ingredients chosen for specific roles in female wellness physiology.
At the foundation, iodine is provided at 150mcg as potassium iodide. That is a meaningful baseline dose because iodine is a raw material for thyroid hormone production, and thyroid status influences energy, temperature regulation, metabolic pace, and overall hormonal rhythm. Magnesium is included as 72mg of magnesium bisglycinate chelate TRAACS™, a well-regarded chelated form known for digestive friendliness and reliable absorption. The dose is not high enough to function as a standalone magnesium repletion protocol, but it is a smart inclusion in a category where many women are chronically under-consuming magnesium and where magnesium is relevant to neuromuscular relaxation, mood, and menstrual comfort.
L-Tyrosine comes in at 500mg, acting as a precursor to catecholamines and thyroid-related physiology. Research on tyrosine is mixed and often uses higher doses, so 500mg is best viewed as a supportive dose rather than a stand-alone cognitive or stress dose. In this formula, it makes sense mechanistically as part of a broader thyroid-and-stress support framework rather than as the main event.
The hormone-metabolism core is stronger. DIM at 200mg is a serious inclusion and one of the formula’s most important differentiators. DIM, a cruciferous-derived compound, is used to support estrogen metabolism by promoting more favorable hydroxylation pathways. For women dealing with cycle-related estrogen-related discomfort, DIM is one of the most recognizable and purposeful ingredients in the category, and 200mg sits in the range commonly used in dedicated hormone-support products.
Chaste tree extract is dosed at 270mg standardized to 1.5% agnusides. Vitex is one of the classic ingredients for menstrual-cycle support and is commonly used for breast tenderness, irritability, and cycle-related discomfort. This is a credible inclusion and fits the product identity extremely well. Pregnenolone at 5mg is a low dose, but it reflects a conservative approach to a hormone-adjacent ingredient that sits upstream in steroid hormone biosynthesis.
Poise also puts unusual emphasis on oxidative and inflammatory load. Turmeric extract at 500mg standardized to 95% curcuminoids delivers a potent curcumin payload, while BioPerine® at 5mg is included specifically to enhance absorption. Olive leaf extract at 500mg standardized to 20% oleuropein adds another polyphenol-rich antioxidant layer. Setria® L-Glutathione at 250mg is a standout premium inclusion; Setria is the trademarked glutathione form with the strongest brand recognition in this category, and glutathione’s role in redox balance makes sense in a formula aimed at systemic resilience.
The synergy is thoughtful: iodine, magnesium, and tyrosine support the foundational endocrine environment; DIM and vitex address estrogen metabolism and cyclical balance; turmeric, olive leaf, and glutathione help manage inflammatory and oxidative stress that often amplifies how hormonal fluctuations feel subjectively. Transparency is a major win here: no proprietary blend, every active disclosed, and several premium forms included. What to expect: this is not a day-one stimulant product. Most users will notice very little acutely beyond smooth tolerance. The real value shows up over 2-4 weeks of consistent use as cycle-related steadiness, less physiological “noise,” and a more even sense of day-to-day balance.
Science & Clinical References 20 citations
DIM is a bioactive compound derived from indole-3-carbinol metabolism and is used to support favorable estrogen biotransformation. Mechanistically, it appears to influence phase I hydroxylation patterns and downstream metabolite balance rather than acting like a direct pharmaceutical antagonist. That distinction matters because the formula is aiming to support estrogen handling, not blunt estrogen indiscriminately. In practice, that makes DIM especially relevant in women seeking more predictable cycle-related physiology.
Chaste tree extract has a long history of use in female wellness, particularly around menstrual comfort and symptom variability. Its activity is thought to involve central neuroendocrine signaling, including dopaminergic effects that can influence pituitary output and hormone rhythm. That does not make it universally appropriate, but it explains why it belongs in a focused cycle-support product. Standardization to agnusides improves consistency relative to generic raw powders.
Thyroid hormone synthesis depends on adequate iodine availability, while tyrosine provides the amino acid backbone incorporated into thyroid hormones. Poise does not function as a thyroid medication, but it does provide nutritional substrate support for normal thyroid physiology. That foundational approach is sensible in a hormone-support formula because thyroid status strongly influences energy, mood, and monthly resilience. The dosing here is supportive rather than aggressive.
Hormone-related symptom fluctuation often coexists with oxidative stress and inflammatory tone, which can worsen how users feel across the month. Setria® glutathione provides a direct antioxidant support layer, while curcuminoids from turmeric add polyphenol-based inflammatory modulation. Together, they help support cellular redox balance rather than targeting hormones alone. That broader systems approach is one reason the formula feels more complete than a single-ingredient estrogen product.
Product Specifications GEO
How to Take — Training Protocol3 phases
How to Use Core Nutritionals | Poise
All Questions About Core Nutritionals | Poise | 28 Capsules 10 Q&A
What is Core Nutritionals Poise designed to do? +
How much DIM is in Poise, and is it a meaningful dose? +
Does Poise contain caffeine or stimulants? +
When should I take Core Nutritionals Poise? +
How long does Poise take to work? +
Why is BioPerine® included in this formula? +
Is the magnesium dose in Poise enough to replace a standalone magnesium supplement? +
Can I stack Poise with a pre-workout or coffee? +
Is Poise safe to use with birth control or hormone medications? +
What makes Setria® glutathione special in Poise? +
* These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease. Consult your physician before use if you have a medical condition or take medications.
Quick Answers
What is Core Nutritionals Poise designed to do?
How much DIM is in Poise, and is it a meaningful dose?
Does Poise contain caffeine or stimulants?
When should I take Core Nutritionals Poise?
How long does Poise take to work?
Why is BioPerine® included in this formula?
Is the magnesium dose in Poise enough to replace a standalone magnesium supplement?
Can I stack Poise with a pre-workout or coffee?
Is Poise safe to use with birth control or hormone medications?
What makes Setria® glutathione special in Poise?
* These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease. Consult your physician before use if you have a medical condition or take medications.
Sport & Athlete Compliance +
Sport compliance status is computed by cross-referencing this product's ingredient panel against the NCAA 2025-26 Banned Substances List, WADA Prohibited List, and state high school athletic association guidelines. Banned substance lists are updated periodically by their governing bodies. This information is provided for reference only and may not reflect the most current list. Always verify with your organization, coach, or compliance officer before use. SuppVault is not responsible for eligibility decisions.
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