Myoblox | Loco Pre | 20 Servings

MyoBlox Loco is a high-stim, full-disclosure pre-workout designed around three pillars: nitric oxide-driven blood flow, hard-output training endurance, and a distinctly nootropic style of focus. This is not a one-dimensional caffeine product. The strategy is obvious from the label: build the pump with a 10g nitric oxide base, reinforce repeated-effort performance with clinically relevant beta-alanine and betaine, then layer in a serious central nervous system stack to sharpen attention, drive, and training intent.

The centerpiece is TRILLINE™ at 10,000mg, a citrulline-plus-arginine system. The exact citrulline/arginine split is not disclosed, so that is the one limitation in evaluating it against standalone L-citrulline research. What we can say confidently is that citrulline is one of the most validated NO-support ingredients in sports nutrition, with human data commonly using roughly 3-8g/day. Citrulline raises plasma arginine more reliably than oral arginine alone because it bypasses significant gut and liver metabolism before conversion in the kidneys. In practice, this means better vasodilation, fuller pumps, and improved blood flow during training. The added arginine supports the same pathway, though citrulline is generally the more efficient backbone.

Beta-alanine is dosed at 3,200mg, which is the clinical benchmark used to build muscle carnosine over time. That matters because carnosine buffers hydrogen ions inside muscle tissue, helping delay the burning fatigue that accumulates during repeated high-intensity efforts. Day one, you may notice the familiar tingling sensation. By weeks 2-4 of consistent use, the real benefit is improved tolerance to high-rep sets, short rest periods, and metabolically demanding training.

L-tyrosine at 3,000mg is a standout dose. Tyrosine is a catecholamine precursor, supplying raw material for dopamine and norepinephrine synthesis. In a formula carrying 400mg total caffeine, that matters: caffeine stimulates the system, while tyrosine helps support the neurotransmitter machinery behind sustained focus under stress. Cognizin® citicoline at 250mg adds a second cognitive pathway by supporting acetylcholine synthesis and membrane phospholipid metabolism; this is right in the dose range used in research showing improved attentional performance. Huperzine A 1% at 20mg yields 200mcg Huperzine A, a meaningful acetylcholinesterase-inhibition dose that helps preserve acetylcholine. Together, tyrosine + citicoline + huperzine create a more locked-in, task-focused experience than caffeine alone.

Betaine anhydrous at 2,500mg is another clinically aligned inclusion. This is the dose commonly studied for power output, work capacity, and cell hydration support. Taurine at 2,000mg complements that by acting as an osmolyte involved in cellular hydration and neuromuscular function. nooLVL® at 1,600mg, an inositol-enhanced bonded arginine silicate, adds another well-designed layer for blood flow, perceived energy, and cognitive performance. Research on this category of arginine silicate has shown improvements in blood flow and perceived energy, and it synergizes well with citrulline by supporting a strong arginine-NO environment from multiple angles.

The stimulant system is aggressive: 300mg caffeine anhydrous plus 200mg caffeine citrate for 400mg total caffeine. Caffeine citrate is faster-acting by weight because it is more rapidly available, while anhydrous provides the classic robust pre-workout rise in alertness and drive. Expect a fast onset and a very noticeable peak. Electrolytes from sodium, potassium, and magnesium support hydration status and neuromuscular function, while pine bark extract contributes antioxidant and endothelial support that conceptually complements nitric oxide preservation. AstraGin® is included as an absorption support ingredient. ImmunoLin® is an unusual but interesting addition, bringing serum-derived bovine immunoglobulins that are more commonly discussed in gut-barrier and antigen-binding contexts than classic pre-workouts; at 200mg, it is more of a differentiating add-on than a core purchase driver.

Transparency is a major strength here. There are no proprietary blends hiding stimulant or pump doses, which is increasingly important in a category with too many labels built for marketing instead of evaluation. Day 1, expect fast-rising energy, tingles, sharp focus, and a dense pump. Over 2-4 weeks, the ingredients that reward consistency are beta-alanine for carnosine saturation and, to a lesser extent, the repeat-session value of betaine, taurine, and the overall training-quality improvement that comes from a formula you can actually dose and assess with precision.

How to Use MyoBlox | Loco | Pre-Workout