NutraBio | Quiet Mind | 30 ServingsNutraBio
- SuppVault Score
- 97/100
- Per serving
- $1.5

NutraBio
Clinical calm from KSM-66®, Holixer™, Relissa®, and Zembrin®
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Quiet Mind is a fully disclosed calm-focus nootropic built to lower stress without flattening you. It combines adaptogens, relaxed-alertness support, and targeted mood ingredients for smoother focus and decompression. KSM-66® Ashwagandha is dosed at a full 600mg clinical level.
NutraBio publishes test results from independent third-party labs. Svpplements links to the manufacturer’s data — we don’t test products ourselves.
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Magnesium glycinate pairs naturally with Quiet Mind because magnesium supports neuromuscular relaxation and healthy nervous-system signaling, while the glycinate form is well suited to evening use. It complements the GABA-supportive feel of L-Theanine and Relissa® and can help round out a more complete wind-down routine.
Take with Quiet Mind in the evening or before bed.
Creatine is usually thought of for strength, but it also supports brain energy metabolism through phosphocreatine availability. That makes it a smart pairing for users taking Quiet Mind for calm cognitive performance under stress, especially students, professionals, and hard-training adults under high total load.
Take daily at any time; it does not need to be taken simultaneously with Quiet Mind.
Stress and poor recovery often coexist with underhydration, which can worsen perceived fatigue, tension, and cognitive drag. A quality electrolyte product helps support fluid balance and nervous-system function while Quiet Mind handles the neurochemical and adaptogenic side of the equation.
Use earlier in the day or around training; Quiet Mind can be taken separately when you want composure.
Quiet Mind helps manage stress chemistry, but it is still important to cover the basics of recovery. Consistent protein intake supports muscle repair, satiety, and overall resilience, which indirectly improves how well you handle stress and maintain performance when life is demanding.
Use post-workout or wherever it best helps you hit daily protein targets.
Quiet Mind offers broader calm, mood, and relaxed-focus support than standalone ashwagandha.
Quiet Mind is more clinically layered for stress resilience and mood support.
5-HTP is the better pick if your main goal is sleep support over daytime calm.
Smooth leans harder into cognition, while Quiet Mind leans harder into stress and mood balance.
Side-by-side against the closest competitors. Score reflects clinical dosing, transparency, and testing.
NutraBio | Quiet Mind | 30 ServingsNutraBio
NutraBio | KSM-66 | 60 ServingsNutraBio
Quiet Mind offers broader calm, mood, and relaxed-focus support than standalone ashwagandha.
Compare side-by-side →
NutraBio | Calm | 30 CapsulesNutraBio
Quiet Mind is more clinically layered for stress resilience and mood support.
Compare side-by-side →
NutraBio | 5-HTP | 90 ServingsNutraBio
5-HTP is the better pick if your main goal is sleep support over daytime calm.
Compare side-by-side →Comparison data combines live storefront pricing with our SuppVault analysis. Competitor scores reflect public-label data; manufacturer-side changes may not be reflected in real time.
NutraBio Quiet Mind is not a generic “calm blend.” It is a fully disclosed, trademark-heavy stress and mood formula built around two parallel goals: reduce the physiological burden of stress and improve the subjective experience of mental calm without turning you into a zombie. The formulation strategy is smart. Instead of relying on one sedating ingredient, NutraBio combines adaptogens for HPA-axis regulation, amino support for relaxed alertness, phytosomal botanicals for GABA support, and targeted mood ingredients that work on serotonin and PDE4 pathways.
The anchor is KSM-66® Ashwagandha at 600mg, a full clinical dose and the top end of the researched 300-600mg range. KSM-66 is a full-spectrum root extract standardized to 5% withanolides and backed by 24 randomized, double-blind, placebo-controlled trials. Mechanistically, it helps regulate the hypothalamic-pituitary-adrenal axis and lowers cortisol while also influencing GABAergic tone. What that means in practice: less wired-but-tired tension, better stress resilience, and often better sleep quality over time.
Holixer™ Holy Basil at 250mg is another standout because 250mg is the exact clinically studied dose. This extract is standardized to a defined Ocimum-Bioactive Complex and has research showing meaningful reductions in perceived stress and stress biomarkers, including hair cortisol, in as little as two weeks. It complements ashwagandha by addressing both acute sympathetic stress responses and chronic stress load.
L-Theanine at 200mg sits right in the sweet spot of the clinical 100-400mg range. It crosses the blood-brain barrier, increases alpha-wave activity, and supports GABA, serotonin, and dopamine while damping excessive glutamatergic firing. The experience is not sedation; it is smoother thinking, reduced mental friction, and a calmer internal tempo.
Relissa® Melissa Phytosome™ at 200mg is another clinically aligned inclusion. Lemon balm is already respected for calming effects, but the Phytosome™ delivery system matters because phospholipid complexing improves dispersion and absorption of key compounds like hydroxycinnamic acids. Its primary mechanism is inhibition of GABA transaminase, which helps preserve GABA activity. Users typically notice emotional softening, less edge, and better evening composure.
Magnolia extract at 100mg standardized to 90% honokiol plus magnolol is a potent supporting piece for acute calm. While magnolia does not have the same clean clinical dose consensus as the major anchors here, 100mg of a highly concentrated extract is a serious inclusion, not a label decoration. Honokiol and magnolol are associated with relaxation and stress relief, making this a sensible low-dose amplifier rather than a primary pillar.
LANDKIND® Salidroside at 30mg is the one ingredient here that lands below the 60mg dose best supported in the provided research. That said, salidroside is a highly studied Rhodiola bioactive, and even at 30mg it likely contributes subtle adaptogenic and mood-resilience support, especially in a multi-pathway formula like this. Zembrin® at 25mg is right at its researched dose and adds something unique: serotonin reuptake inhibition plus PDE4 inhibition. That combination supports mood, stress resilience, and a cleaner sense of mental composure rather than simple sedation.
As a system, this formula covers stress chemistry from multiple angles: cortisol modulation, GABA support, alpha-wave promotion, serotonin signaling, and acute calming phytochemicals. It is also fully transparent with no proprietary blend, which matters in a category full of vague “peace” formulas hiding weak doses. Expect the first serving to feel mentally smoothing within 30-90 minutes, especially from theanine, lemon balm, magnolia, and Zembrin®. Over 2-4 weeks, the heavier adaptogenic effects from KSM-66® and Holixer™ become more noticeable: better stress tolerance, less emotional volatility, and a more stable baseline.
KSM-66® ashwagandha is primarily valued for normalizing stress signaling across the hypothalamic-pituitary-adrenal axis. Human data suggest it can lower perceived stress and reduce cortisol output when chronic stress load is elevated. Mechanistically, its withanolides appear to influence neuroendocrine resilience rather than acting like an acute sedative. That makes it more useful for improving baseline stress tolerance over repeated daily use.
L-theanine promotes a state often described as relaxed attentiveness by modulating excitatory-inhibitory balance in the brain. It is associated with increased alpha-wave activity, which aligns with calm focus rather than stimulation or sedation. The compound may also buffer the subjective sense of mental tension during cognitively demanding tasks. In practice, that makes it a strong bridge ingredient between productivity and composure.
Holixer™ holy basil is standardized for a defined bioactive complex and is positioned for both acute and chronic stress support. Its actives appear to influence oxidative stress, inflammatory tone, and neuroendocrine signaling linked to perceived stress burden. Clinical work with this specific extract has shown improvements in stress markers and subjective stress scores. It functions more like a resilience-support botanical than a simple calming herb.
Relissa® uses a phytosome delivery approach to improve absorption of lemon balm constituents, particularly hydroxycinnamic acids. Lemon balm is often discussed for its influence on GABA metabolism and inhibitory neurotransmission, which may help reduce agitation and mental overactivity. The phytosomal format is relevant because delivery can meaningfully affect real-world response at modest doses. This makes it useful for smoother onset calm without overwhelming sedation.
Zembrin® is a standardized Sceletium tortuosum extract studied for effects on mood, stress reactivity, and emotional processing. Its pharmacology is notable because it appears to influence serotonin signaling while also inhibiting PDE4, a mechanism relevant to intracellular cyclic AMP dynamics. That dual activity may help explain why users often describe a more emotionally even state rather than simple drowsiness. It is one of the more targeted mood-support ingredients in the formula.
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* These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease. Consult your physician before use if you have a medical condition or take medications.
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